You are allowed to enrol in single courses at Politecnico for future admission to a Master's degree programme if:
Enrolment in single courses is valid for one academic year only: this implies that if you purchesed a single course but you did not pass the exam by the last examination session of the academic year (September), you will have to enrol again in the single course for the following academic year, paying again the tuition fees for students enrolled in Single courses.
Enrolment in single courses is incompatible with enrolment in other Italian universities: this means that you are not allowed to be simultaneously enrolled in any course at any other Italian university.