0. Aims and some anticipation
0.1 Why and How a responsible R&I
0.2 Responsibility - concrete and workable consequences

1. Why the responsibility in social challenges?
1.1 The limits of our understanding
1.2 The announcement of R&I advances - enthusiasm or mortification?
1.3 Does it make sense to raise some question?
1.4 What can we learn?

2. Organising a discourse around the responsibility in R&I
2.1 The Observer and the Observed process
2.2 Some paradigms for the action
2.3 Language and contaminations
2.4 The responsible choice between past and future

3. Societal challenges, the responsible approach - examples
3.1 Finance and Technology for a never-ending growth?
3.2 Digital communications, physical and cognitive impact
3.3 Digital communications, the social dimension
3.4 The goods production cycle - quantity or quality?
3.5 The food chain, from fork to farm
3.6 Health and care, from reactive to systemic paradigms
3.7 Ageing population - a social bomb?
3.8 Energy conversion - centralisation or de-centralisation?
3.9 Automation, the social dimension
3.10 Disintermediation, the prosumer on the horizon
3.11 The employment dilemma

4. Seeking for new perspectives. The global responsibility
4.1 From Kyoto to COP 21 - a global concertation for a sustainable development?
4.2 The CO2 budget
4.3 Environmental sustainability or social stability?
4.4 Potential measures for prosperity

5. Seeking for new perspectives. The local responsibility
5.1 The local-global dilemma – competition and inclusion
5.2 EU, Community Led Local Development and other measures
5.3 Emerging opportunities for new economic paradigms – re-orientate the technology potentials
5.4 Emerging opportunities for new economic paradigms – identify the synergies within the social issues
5.5 Exploiting the opportunities

6. A responsible education for a responsible mind-set
6.1 Cognitive constructs and responsibility
6.2 Education through societal challenges
6.3 Digital school and employment perspectives

7. Conclusion – a summary, a recommendation and further studies