Materials, particularly their integration into products, e.g., components and complex structures, determine the socio-economical level of high developed and industrialized countries as well as their potentials of growth and technological development. Materials, due to their multiple properties (e.g. mechanical, chemical, physical, metallurgical, etc.) are essential for the innovative development of most engineering sectors. Products performances depend on both material properties and manufacturing processes. Future engineering education is directed towards an ever increasing complexity of products in terms of geometry, material, microstructure or microarchitecture. Their proper design requires highly interdisciplinary fundamental knowledge of materials science, physics, chemistry, strength of materials and compliances with environmental and energy constraints, efficient use of raw materials, customized design thereby making them more difficult to design, produce and optimize while being sustainable. To meet all these challenges, the future design engineer has to master multidisciplinary engineering design with the aid of computer modelling and simulation. Learning of the fundamentals and tools aiding a better understand the relationship between materials properties, component performance, manufacturing and environmental issues is of paramount importance. As the interaction between material and manufacturing process determines the component shape, the latter is then analyzed as a further constraint to the design methodology. Moreover, multidisciplinary complexity impose different design criteria to be combined ssuch that multiple material properties, constrains and objectives need to be solved simultaneously . Thus, the course provides interdisciplinary design methodologies along with flexible software tools, such as GRANTA-ANSYS, to model and solve coupled fundamental-engineering problems related to materials and their interactions under multiple or conflicting constraints. Nearly 70% of te course is devoted to laboratory modeling and training exercise, just 30% theoretical review. The first part deals with the selection of materials and processes aided by the GRANTA-ANSYS software, involving materials the product shape and microstructure. This software allows the student to access a universe of more than 4000 materials and more than 250 manufacturing processes to choose from with their complete list of attributes and qualities respectively. The package is then applied to multidisciplinary design of bulk components of complex cross section and shaped thin sheets under multiple loading (mechanical, chemical, physical, etc.) conditions. More realistic but more complex view of materials can be achieved assuming the change of material microstructure as a variable factor. Appropriate engineering solution methods and computational tools will be developed in the second part of the course using the MathCad software to analyze a wide range of engineering problems. The kinetic models combined to the structural aspects of materials or to the processing phenomena will be analyzed and solved numerically for a number of practical cases. As a whole of both approaches, the student will be able to build an individual” engineering capability “ to problem solving. Numerous case studies to be solved and discussed will be proposed by the teacher or selected by the students taking inspiration from the education profile of the student. Lectures, exercise and laboratories classes are intended to guide the student to understand the case studies, to build own computational tools (flow chart), needed to carry a critical a-posteriori analysis of the results so that the student can strengthen his own desirable “engineering insight”.