Politecnico di Torino
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Politecnico di Torino
Academic Year 2017/18
01OBDOQ, 01OBDMV
Bio-Micro&Nano Systems
Master of science-level of the Bologna process in Electronic Engineering - Torino
Master of science-level of the Bologna process in Biomedical Engineering - Torino
Teacher Status SSD Les Ex Lab Tut Years teaching
Demarchi Danilo ORARIO RICEVIMENTO O2 ING-INF/01 42 9 9 0 10
SSD CFU Activities Area context
ING-INF/01 6 B - Caratterizzanti Ingegneria elettronica
Subject fundamentals
The course is taught in English.
The module Bio-Micro&Nano Systems aims to develop the knowledge of Micro&Nano Electro Mechanical Systems (MEMS and NEMS) for the various applications in the fields of Biology, Medicine and BioMolecular Chemistry. Fabrication processes are reviewed and studied with details, giving emphasis to more specific topics as MicroFluidics, Packaging and BioMolecule integration in micro and nanostructures produced with various materials, as silicon, glass, plastics and polymeric substrates. Industrial applications are presented from biosensors, and their transduction techniques, up to systems for biomolecular analysis, passing to the study of the micro and nanostructures more related to basic research. Particular emphasis is given to practical and design aspects, and the student use CAD tools for the application of acquired knowledge and the design of a simple micro/nano system.
Inside the course, seminars held by experts of biomedical applications, both from industries and from international research centres, are organised.
Expected learning outcomes
The student in the module of Bio-Micro&Nano Systems has the possibility to apply and extend the knowledge of micro and nano technologies, focusing on their applications in BioMedicine and BioMolecular applications in general. The work during the module mixes theoretical aspects with design methodologies, in fact one of main training tasks consists in giving to the students the necessary tools for the design of micro and nano structures for bio-applications.
Prerequisites / Assumed knowledge
Basic knowledge of microtechnologies, of physics of materials and chemistry, as acquired in the general study track.
Contents
After an introduction to micro and nano systems for BioMedicine, the course is focused on review and goes in details in the technologies for the design and the realization of microelectronic devices, as technological starting point. Then the focus moves to the technological evolution from which the solutions for the production of micro and nano systems were born. The main topics are:
- basic concepts of techniques and materials for micro and nano systems;
- the specific approaches for realizing biological applications, as for example microfluidics;
- an introduction to the design flow and the CAD instruments disposable on the market;
- the study of applications, with particolar focusing on biosensore;
- study and development of more complex systems for biomedical applications.

A quite large part of the course is focused on learning the CAD softwares Comsol and CoventorWare, with which are realized laboratories with, as final result, the design of simple Micro/Nano Systems.

The structure of the course is:
** Introduction to the Course and to the Technologies (2 CFU)
- Microelectronics Technologies
- Technologies of Micro/Nano systems
- Industrial Technologies for MEMS
** Useful techniques for the realisation of Bio-MEMS/NEMS (2 CFU)
- Microfluidics
- Basic Concepts of Electrochemistry for Biosensors
- Packaging
** Design of Bio-MEMS/NEMS (2 CFU)
- Biosensors
- CAD for microsystems: theory and laboratory
- Example of designs of Bio-MEMS-NEMS and autonomous design of a simple Bio-MEMS/NEMS
Delivery modes
The course considers a work using CAD tools for Microsystems, as Comsol and CoventorWare, for allowing the design and the simulation of simple MEMS/NEMS, carried out in groups. The laboratory sessions (at least 12 hours) will be associated to a further personal work thanks to the access to Politecnico laboratories where the student will design some simple microsystems, reported for the final exam. It is considered a visit to Chilab/MiNES (Micro&Nano Electronic Systems Laboratory) of Politecnico di Torino, where are present a clean room and the tools useful for Micro/Nano System realization, interface and characterization.
Texts, readings, handouts and other learning resources
On the 'Portale della Didattica' will be downloadable:
- The course slides
- Design kits of some industrial technologies
- Tutorials for Comsol and CoventorWare CAD tools
- For more information, application examples and videos related to course topics

Useful books:
- Stephen D.Senturia, MICROSYSTEM DESIGN, Kluwer Academic Publishers
- S.M.Sze, SEMICONDUCTOR SENSORS, John Wiley & Sons
- S.Carrara, BIO/CMOS INTERFACES AND CO-DESIGN, Springer

eLearning material based on the European project EduNano (http://edunano.eu). Access credentials will be given during the course.
Assessment and grading criteria
The assessment is based on an oral examination, with the presentation of the work done and the detailed study of some devices and aspects related to micro and nano technologies for bio-applications, prepared and chose by the student. The mark is based on the acquired competences and on the design autonomy demonstrated by the student.

Programma definitivo per l'A.A.2016/17
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