Molecular optimisation of the sour taste receptor candidates: a study on the Otopetrin family
Parole chiave MOLECULAR COMPUTING, MOLECULAR DYNAMICS
Riferimenti MARCO AGOSTINO DERIU
Gruppi di ricerca 28- biomedica
Tipo tesi MASTER THESIS
Descrizione This research project supervised by Prof. Marco Agostino Deriu is focused on the investigation of taste perception at the molecular level and it is inserted into an EU-funded project, called VIRTUOUS (https://virtuoush2020.com/), aimed at developing an integrated computational platform working as a virtual tongue able to predict the organoleptic profile of the Mediterranean ingredients. The basic idea behind the VIRTUOUS platform is the integration of different levels of investigation ranging from the molecular level (computational modeling, drug discovery, etc.), up to machine learning classifiers, algorithms for big data, cloud computing, and finally experimental data to predict the taste of specific foods based on their chemical composition.
For further information about the specific work proposed here, please contact via email directly Prof. Marco Deriu (firstname.lastname@example.org), inserting in CC the PhD student Lorenzo Pallante (email@example.com).
Vedi anche thesisproposals.docx
Conoscenze richieste It is required that the student has taken Professor Deriu's "Biomeccanica Multiscala" course and has acquired good basic knowledge of the bash language and GROMACS. Attendance at "Biomechanical Design" and "Rational Drug Design" courses by Prof. Jack Tuszynski is also very welcome.
Scadenza validita proposta 26/04/2023 PROPONI LA TUA CANDIDATURA