Comprehensive evaluation of docking algorithms on peptide drugs
Riferimenti JACEK ADAM TUSZYNSKI
Riferimenti esterni Prof. Gane Wong, Department of Biological Sciences, University of Alberta, Edmonton, Canada
Gruppi di ricerca 28- biomedica
Tipo tesi COMPUTATIONAL
Descrizione Peptide drug development has made great progress in the last decade and a wide variety of natural and modified peptides have been obtained and studied; remarkable achievements have been made resulting in the approval of more than 80 peptide drugs worldwide. The development of peptide drugs has thus become one of the hottest topics in pharmaceutical research. A performance evaluation of the current state-of-the-art peptide-protein docking algorithms on approved peptide drugs is therefore crucial to assess the quality of computational predictions.
Conoscenze richieste basic bioinformatics, computational modeling, molecular dynamics, docking
Scadenza validita proposta 04/02/2024 PROPONI LA TUA CANDIDATURA