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The UV-Induced Maturation of Ergosterol into Ergocalciferol (Vitamin D2)

estero Tesi all'estero


Parole chiave ERGOSTEROL, FERMENTATION, FUNGI, VITAMIN D2

Riferimenti FRANCESCA BOSCO

Riferimenti esterni Ing Carlos Gomez Camacho (EMPA)

Tipo tesi EXPERIMENTAL

Descrizione Vitamin supplementation is crucial, particularly for people on specific diets that may provide lower levels of essential micronutrients, such as vitamin D. While the most studied form of vitamin D is D3 (cholecalciferol, primarily derived from animals), vitamin D2 (ergocalciferol) has gained increasing attention due to its plant, algal or fungal-based origin, making it more suitable for alternative diets and for its potential use in food fortification. This thesis aims to conduct laboratory experiments to study the photochemical maturation of ergosterol into vitamin D2. The research will involve both in vivo studies (using different fungal species) and in vitro studies (using ergosterol extracted from fungi). The experimental work includes cultivating various fungal species, exposing mycelium, fruiting bodies, and ergosterol-rich fungal lipid extracts to UV radiation to observe the dynamics and kinetics of this conversion process.

Conoscenze richieste • Biotechnology - fungi cultivation (high share of experimental work, detail-oriented required)
• Chemical Engineering – Extraction techniques
• Chemical Engineering – Advanced characterization techniques


Scadenza validita proposta 03/09/2025      PROPONI LA TUA CANDIDATURA