| KEYWORD |
Exploration of genetic regulatory mechanisms at the pathway level
keywords BIOINFORMATICS, STATISTICS, SYSTEMS BIOLOGY
Reference persons ALFREDO BENSO, STEFANO DI CARLO
External reference persons GIANFRANCO POLITANO (gianfranco.politano@polito.it)
ALESSANDRO SAVINO (alessandro.savino@polito.it)
Research Groups SYSTEMS BIOLOGY GROUP
Thesis type RESEARCH, INNOVATIVE
Description In the past few years, the quest for recurrent motifs in the complex world of gene regulation achieved several interesting results and the regulatory role of non-coding RNAs (http://it.wikipedia.org/wiki/MicroRNA) in intra- pathway regulation is under constant investigation. The goal of this thesis is the identification of regulatory motifs by complex data mining approaches on integrated data from several online repositories.
See also http://www.ncbi.nlm.nih.gov/pubmed/24152805
Required skills C/C++ programming, SQL, scripting languages
Notes The thesis may require to study basic concepts of biology.
Deadline 31/10/2014
PROPONI LA TUA CANDIDATURA