| KEYWORD |
Acquisition of the electrical activity of neurons for neurodegenerative diseases through diamond microelectrode arrays (MEAs)
keywords CELL CULTURES, MEAS, NEUROSCIENCE, PCB
Reference persons DANILO DEMARCHI
External reference persons Alessandro Sanginario (alessandro.sanginario@polito.it),
Research Groups MiNES (Micro&Nano Electronic Systems)
Thesis type EXPERIMENTAL
Description Improving the quality of the research in neuroscience is a fundamental step to find efficient strategies for the treatment of neurodegenerative disorders, such as Parkinson’s disease or Alzheimer’s.
The thesis work is based on the design and the development of electronic interfaces to record signals coming from neuronal cell cultures by innovative diamond-based MEAs. After a preliminary phase of study, the applicant will need to find solutions to develop the electronics of the system, aiming to produce PCBs able to level up and improve the current devices. Eventually, the system will be tested on real cell cultures at the neuroscience laboratory. The results will be digitally processed and statistically analysed.
Required skills Basics of analog circuit design, Basics of microcontroller programming, Signal processing
Deadline 21/11/2023
PROPONI LA TUA CANDIDATURA